Research Papers

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    Cyclin D1expressionamongcolorectalcancerpatients
    (Asian Journal of Health Sciences, 2022) Salih, Hanaa Ibrahim; Elsheikh, Mohammed Abdelgader; Idris, Alkhair Abd Almahmoud
    Background: Cyclin D1 plays a vital role in cancer cell cycle progression and it is overexpressed in manyhumancancers,includingcolorectalcancer. ThisstudyaimedtodetectcyclinD1incolorectal cancer patients and to correlate cyclin D1 expression with different pathological changes in the colorectum. Methods: Tissue microarray paraffin blocks with 48 colorectal cancer samples were retrieved from the archives of Elrahma Medical Center. Cyclin D1 was analyzed. Results: Cyclin D1 did not correlate with pathological alterations or with a particular tumor grade. Conclusion: The results indicate that cyclin D1 does not correlate with pathological alterations in colorectal cancer

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