Research Papers
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Item ESTIMATION OF SERUM TRIIODOTHYRONINE (T3), THYROXIN (T4) AND THYROID STIMULATING HORMONE (TSH) IN CIGARETTE SMOKERS IN KHARTOUM STATE(International Journal of Current Multidisciplinary Studies, 2018) Hamdan,Malak M.Bakhit; Adam,Jasim M; Sulliman,Mawaheb Abdullah; Haider,Harith; Mohamed,Ahmed; Abdallah,RehamIzzaldeen; Maaz,Rana; Mohamed,Mazin S. A; Abdelgader,MohamedBackground: Cigarette smoking has a number of effects on the thyroid gland including the development of Graves’ disease and thyroid multi-nodularity. However, the effect of smoking on thyroid function is more uncertain. This study aimed to estimate the levels of thyroid hormones in cigarette smokers Materials and Methods: This study was designed as acase-controlon80 participants,40 of who were smokers as case and 40 were non-smokers as control in Khartoum State (2016- 2017). Serum T3, T4 and TSH were measured by ELISA (Enzyme-Linked Immunosorbent Assay) (URIT-660 micro-plate reader made in China serial number 66001674 E) Results:Were expressed as: (Mean +SD) and sig-2 tailed Pearson: Serum T3 level in smokers was (.063 ng/ml+ 0.18); in non-smokers was (1.48ng/ml + 0.26) and a p value of 0.0000001; T4 level in smokers was (2.75μg/dl + 0.67); in non-smokers was (5.79μg/dl +0.60) and a p value of 0.000000, and TSH level in smokers was (0.62 μIU/ml + 0.38); in non-smokers was (0.38μIU/ml +0.08) and p value of 0.009. Conclusion: Serum T3 and T4 levels in Sudanese smokers was decreased when compared to the levels in non-smokers. WhereasTSH levels were similarItem Measurement of Lipid Profiles in Patients with Acute Myocardial Infarction in Different Anti-Coagulants(International Journal of Pharmacy and Biological Sciences, 2014) Maaz,Rana; Dafalla,Mustafa; Khogali,Tawfig; Mahdi,Mohammed A; Modawe,Gad AllahBackground: Myocardial infraction is the death of heart muscle from the sudden blockage of coronary arterial vessel by a blood clot. Objectives: The aim of this study was to measure plasma/serum lipid concentrations in patients with Acute Myocardial Infraction (AMI) within one week of onset of symptoms of AMI in different anti- coagulates. Methodology: This study was case-control study, match age and sex, carried out in Alshab Teaching Hospital at Khartoum State in period from March to August 2007. Blood samples were collected in all subject study (patients and controls) and estimated the lipids in serum and plasma by colorimetric methods. Results: The (mean ±SD) serum/plasma cholesterol in patients were (162.43±33.78, 161.33±44.37, 161.10±46.94) and also in control subject were (161.43±42.08, 162.80±38.29, 167.70±4.43) respectively. The (mean ±SD) of serum/plasma triacylglycerol in patients and control were respectively (105.30±52.53, 11.70±49.61, 113.70±55.80) in controls were (112.70±57.17, 110.83±54.17, 105.93±42.25). The (mean ±SD) in serum/plasma high density lipoprotein in patients were (41.93±15.95, 38.10±13.65, 36.83±13.31) in control were (112.70±20.95, 110.83±19.63, 105.93±17.09). The (mean ±SD) in patients of low obesity lipoproteins were (99.73±43.27, 100.57±51.58, 102.63±51.25) and also control were (85.10±38.167, 92.93±22, 102.93±47.95) comparison between WHO recommended anti-coagulant (EDTD, Lithium heparin) LDL levels showed a significant difference (P=0.039) in plasma for lithium heparin as anti-coagulant, but HDL showed statistical difference (P=0.0) in both serum and plasma with EDTA. Conclusion: From this study it could be concluded that it might be better to use serum in the measurement of lipid profile than use anti-coagulant (EDTA and lithium heparin).